Tag Archives: Horrible Disease

Question?: Rett Syndrome

John asks…

Why are diseases that are found to be curable/reversible in mice?

not in humans?

Serious answers only please.

Asking b/c Rett Syndrome ( a devastating neurological disorder) was completely reversed in mice like 3 years ao & I don’t understand why the same basic concepts that made that possible can’t be used in living humans suffering from this horrible disease

OCTOBER IS RETT SYNDROME AWARENESS MONTH
Care Today-Cure tommorow !

admin answers:

Great question and thanks for posting about Rett Syndrome and helping raise awareness!

In the experiments on mice (1 1/2 yr ago) they silenced the MECP2 in the mice (with insertion of a “stop cassette”), and then un-silenced it to see if the effects would be permanent like they believed they would be. So the mice didn’t actually have Rett Syndrome and in RS there is no “stop cassette” built into it to turn on again. So the real outcome of this study showed that once a cure/treatment is found, these girls could possibly be normal again and not neurologically damaged permanently…this is amazing in itself but doesn’t mean we are any closer to a cure.

Powered by Yahoo! Answers

Question?: Rett Syndrome Awareness Month

Helen asks…

Why are diseases that are found to be curable/reversible in mice?

Serious answers only please.

Asking b/c Rett Syndrome ( a devastating neurological disorder) was completely reversed in mice like 3 years ao & I don’t understand why the same basic concepts that made that possible can’t be used in living humans suffering from this horrible disease

OCTOBER IS RETT SYNDROME AWARENESS MONTH
Care Today-Cure tommorow !
I meant to write : Why are diseases that are found to be curable/reversible in mice not curable in Humans

admin answers:

Partly because treatments which work on mice models do not always work on humans, since we are obviously not the same animals. Also, there is a big problem with getting clearance to use a treatment on humans. It has to pass so many types of rules and regulations, and then it can be used in clinical trials. Then there has to be placebo groups studied and so on and so on. Then it has to go through more rules and regulations. Salk said that if he were to submit his vaccine to the powers that be today, the cure would still be tied up in paperwork and obstacles.

Powered by Yahoo! Answers

Question?: Rett Syndrome Awareness Month

Laura asks…

Why are diseases that are found to be curable/reversible in mice?

Serious answers only please.

Asking b/c Rett Syndrome ( a devastating neurological disorder) was completely reversed in mice like 3 years ao & I don’t understand why the same basic concepts that made that possible can’t be used in living humans suffering from this horrible disease

OCTOBER IS RETT SYNDROME AWARENESS MONTH
Care Today-Cure tommorow !
I meant to write : Why are diseases that are found to be curable/reversible in mice not curable in Humans

admin answers:

Liberalism is currently curable with large amounts of knowledge in most mammals.

Powered by Yahoo! Answers